| （School of Physical Education，Gannan Normal University，Ganzhou 341000，China） Abstract: In order to study the effects of intermittent exercising on the gene expression of adrenal medullarin (ADM) receptor activity modifying protein 2 (RAMP2) and calcitonin receptor like receptors (CRLR), which con-stitute particular ADM receptors, and to explore the functioning mechanism of ADM in intermittent exercising in-ducing cardiac muscle cell protection, the authors divided 30 SD rates into a control group (group C) and an inter-mittent exercising group (group IE), let the rats in group IE do a 3-week intermittent treadmill exercise, applied real time fluorescent quantified reverse transcription polymerase chain reaction (RT-PCR) to test the expression of par-ticular ADM receptors RAMP2 and CRLR, and revealed that the levels of expression of RAMP2 mRNA and CRLR mRNA of the rats in group IE increased significantly, which indicates that intermittent exercising increases the gene expression of particular ADM receptors, can increase the contents of particular ADM receptors in cardiac muscle tissues, and that the functions of ADM on the heart are enhanced by the increase of particular receptors, which plays an important role in strengthening cardiac muscle contraction, dilating coronary arteries, ensuring cardiac muscle functions and coronary artery blood flow, as well as maintaining hemodynamic stability and protecting cardiac mus-cle cells during exercising.
Key words: sports biochemistry；intermittent exercise；adrenal medullarin；receptor activity modifying protein 2；calcitonin receptor like receptor；gene expression |
